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The two-term governor announced on his Twitter account that he would seek the 2016 Republican nomination.
Jindal, the country's first elected Indian-American governor, joins a crowded GOP field featuring 98 officially listed candidates, from former Florida Gov. Jeb Bush to Donald Trump.
The latest NBC/Wall Street Journal poll hints that Jindal will have his work cut out for him as he currently sits outside the top 10 Republican candidates. The Louisiana governor stands three spots behind Donald Trump in 14th place with less than 1 percent of Republican respondents indicating that he would be their first choice for the nominee.
On the plus side, Jindal still has some upside in the eyes of GOP supporters.
More Republican voters can see themselves voting for him than not, by an 8 percent margin. However, that upside pales in comparison to front runners such as Bush (53 percent positive margin) and Florida Sen. Marco Rubio (59 percent positive margin.)
—The AP contributed to this report.