LEXINGTON, Mass., Sept. 9, 2015 (GLOBE NEWSWIRE) -- Aldeyra Therapeutics, Inc. (Nasdaq:ALDX) (Aldeyra), a biotechnology company focused on the development of products to treat diseases related to free aldehydes, today announced that novel data on the potential of its lead product candidate, NS2, to treat Succinic Semi-aldehyde Dehydrogenase (SSADH) Deficiency have been accepted for a poster presentation at the upcoming American Society of Human Genetics (ASHG) Annual Meeting, which will take place in Baltimore, Maryland from October 6-10, 2015.
Succinic Semi-aldehyde Dehydrogenase (SSADH) Deficiency is a rare disease caused by mutations in SSADH, leading to elevated levels of succinic semi-aldehyde that are then converted to neurotoxic metabolites. SSADH Deficiency is characterized clinically by neurological compromise that includes cognitive and developmental delay, decreased muscle tone, and, in some cases, seizures.
The poster title and date of the presentation are provided below:
|Title:||The small molecule aldehyde trap NS2 represents a pharmacological approach to enzyme replacement therapy for SSADH deficiency (SSADHD)|
|Date:||Thursday, October 8th|
|Time:||11:00 a.m. – 12:00 p.m. E.T.|
Todd C. Brady, M.D., Ph.D., President and CEO of Aldeyra, commented, "The acceptance of this poster at the ASHG annual meeting represents a significant milestone for the Company as SSADH Deficiency represents the second inborn error of aldehyde metabolism that we intend to treat with NS2. SSADH Deficiency is a rare but serious disease with no FDA-approved therapy. The initial data with NS2 suggest the potential of aldehyde trapping as a novel therapeutic approach."
NS2 is an aldehyde-binding small molecule based on an innovative platform technology focused on trapping free aldehydes, which are toxic and pro-inflammatory mediators of numerous diseases. By decreasing aldehyde load, NS2 may mitigate excessive inflammation and address diseases where aldehydes are thought to mediate pathology.
About Aldeyra Therapeutics
Aldeyra Therapeutics, Inc., is a biotechnology company focused primarily on the development of products to treat diseases thought to be related to endogenous free aldehydes, a naturally occurring class of toxic molecules. The company has developed NS2, a product candidate designed to trap free aldehydes. Aldeyra has initiated clinical testing of NS2 for the treatment of Sjögren-Larsson Syndrome and noninfectious anterior uveitis and intends to initiate clinical testing in allergic conjunctivitis. NS2 has not been approved for sale in the U.S. or elsewhere. www.aldeyra.com
Safe Harbor Statement
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In addition to the risks described above and in Aldeyra's other filings with the SEC, other unknown or unpredictable factors also could affect Aldeyra's results. No forward-looking statements can be guaranteed and actual results may differ materially from such statements. The information in this release is provided only as of the date of this release, and Aldeyra undertakes no obligation to update any forward-looking statements contained in this release on account of new information, future events, or otherwise, except as required by law.
CONTACT: Corporate Contact: Stephen Tulipano Aldeyra Therapeutics, Inc. Tel: +1 781-761-4904 Ext. 205 email@example.com Investor Contact: David Burke The Ruth Group Tel: +1 646-536-7009 firstname.lastname@example.orgSource:Aldeyra Therapeutics