Cramer said he made two huge mistakes last year: First was selling Home Depot from his charitable trust, and the second was cutting Tom Brady from his fantasy football team. They both ended up making monster runs for the Super Bowl.
"I recognize that it is fashionable in fantasy circles to not draft a top quarterback early. Just like it's not fashionable in the stock game to stick with a domestic retailer that's linked to the cyclical home business," the "Mad Money" host said.
But in Cramer's opinion, both Tom Brady and Home Depot make the most out of what they have. That is why Brady wins Super Bowls and why Home Depot manages to rise above its retail competition year after year.
And while Cramer has championed Home Depot for a long time, he does recognize that he has too often played the Fed game with the stock, saying that it will go down the hardest if the Fed raises rates—that has been a mistake.
"While housing will be hurt by any increase in mortgage rates, I just don't think Home Depot's numbers will come down. Therefore, the stock is a buy. I think it's exactly the kind of quarterback your portfolio needs," Cramer said. (Tweet This)
Read More Cramer's fantasy football portfolio: Top QB pick
At a time when there is so much volatility happening overseas, Cramer says investors need to pay attention to foreign currency exchange rates versus the U.S. dollar.
After all, a strong dollar has the ability to wreak major havoc on all U.S.-based international companies because when they translate sales from weak currencies overseas, that could mean fewer dollars.
"If you're not paying attention, these currency issues can come out of nowhere and body slam your portfolio," the "Mad Money" host said.(Tweet This)
In addition, Cramer thinks that Thursday's Federal Reserve decision of whether to hike interest rates could have major impact on currencies around the globe. To get a better sense on where the currency markets could be headed, Cramer spoke with Bob Lang, a technician, founder and senior strategist at ExplosiveOptions.net as well as Cramer's colleague at RealMoney.com.
Ultimately, Lang thinks that investors should not sweat the upcoming Fed meeting. And if the Fed does not raise rates, this could cause the euro, and even the yen, to roar.
"I think this is a huge call and, again, I remind you that if the dollar gets weaker then 2016 earnings estimates for all but the pure domestic companies will be going higher, which is something that could knock this bearish phase for so many international stocks right off its tracks," Cramer said. (Tweet This)
Read More Cramer: Fed meeting could trigger a USD bodyslam