BioRestorative Therapies Announces Patent Granted for Its Licensed Curved Needle Device

MELVILLE, N.Y., Nov. 3, 2015 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. ("BRT" or the "Company") (OTCQB:BRTX), a life sciences company focused on stem cell-based therapies, today announced that the Company is the beneficiary of a patent granted for a licensed curved needle device ("CND") designed to deliver cells and/or other therapeutic products or material to a site having damage in need of facilitated repair.

The claims of the patent relate to devices and methods for optimized or facilitated delivery of therapeutics to a target site in a patient in need of a biologic therapeutic. The Company intends to advance the design of this curved needle device to facilitate the delivery of substances, including living cells, to specific locations within the body and minimize the potential for damage to nearby structures.

The device relies on the use of pre-curved nested cannulae that allow cellular and other therapeutics to be deposited in areas where direct access is not possible due to outlying structures (e.g., vertebra, spinal cord and spinal nerves with regard to the disc).

The therapeutic delivery device patent was issued to BRT's licensor, Regenerative Sciences, LLC ("Regenerative"), on August 25, 2015. Pursuant to a license agreement, BRT has obtained a worldwide, exclusive, royalty-bearing license from Regenerative to utilize or sublicense the medical device for, among other purposes, the administration of specific cells and/or cell products to the disc and/or spine (and other parts of the body).

About BioRestorative Therapies, Inc.

BioRestorative Therapies, Inc. ( develops therapeutic products and medical therapies using cell and tissue protocols, primarily involving adult stem cells. Our two core programs, as described below, relate to the treatment of disc/spine disease and metabolic disorders:

• Disc/Spine Program: Our lead cell therapy candidate, brtxDISC™ (Disc Implanted Stem Cells), is a product formulated from autologous (or a person's own) cultured mesenchymal stem cells collected from the patient's bone marrow. We intend that the product will be used for the non-surgical treatment of protruding and bulging lumbar discs in patients suffering from chronic lumbar disc disease. The treatment involves collecting a patient's own stem cells, culturing and cryopreserving the cells, and then having a physician inject brtxDISC™ into the patient's damaged disc in an outpatient procedure. The treatment is intended for patients whose pain has not been alleviated by non-invasive procedures and who potentially face the prospect of surgery.

• Metabolic Program (ThermoStem®): We are developing an allogeneic cell-based therapy to target obesity and metabolic disorders using brown adipose (fat) derived stem cells to generate brown adipose tissue ("BAT"). BAT is intended to mimic naturally occurring brown adipose depots that regulate metabolic homeostasis in humans. Initial preclinical research indicates that increased amounts of brown fat in the body may be responsible for additional caloric burning as well as reduced glucose and lipid levels. Researchers have found that people with higher levels of brown fat may have a reduced risk for obesity and diabetes. The Company is a party to a research agreement with Pfizer with regard to the study of brown fat.

Forward-Looking Statements

This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events or results to differ materially from those projected in the forward-looking statements as a result of various factors and other risks, including those set forth in the Company's Form 10-K filed with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and the Company undertakes no obligation to update such statements.

CONTACT: Lee Roth / Joseph Green The Ruth Group for BioRestorative Therapies 646-536-7012 / 7013 / jgreen@theruthgroup.comSource:BioRestorative Therapies