"There's a lot of nervousness in the air and investors are selling first and asking questions later," said Adam Sarhan, CEO of Sarhan Capital.
Health care, telecommunications and consumer discretionary were the only advancers in the S&P 500, which briefly joined the Nasdaq composite in positive territory for 2015 in intraday trade. The Dow Jones industrial average is still more than 1 percent lower year-to-date.
"The gains from Home Depot has helped. (It shows) the consumer is spending in select areas. I think it's also a slight continuation of yesterday," said Robert Pavlik, chief market strategist at Boston Private Wealth. He has holdings in Home Depot but not Wal-Mart.
"The market is probably going to trade somewhat in lockstep with oil," Pavlik said. He expects crude to bottom near $30 a barrel and said investors are increasingly focused on crude's struggle to stay above $40 a barrel.
Energy ended more than 1 percent lower, following a reversal in oil prices after Monday's gains.
"I think basically the market is reflecting the fact now the Fed comes back into play and oil prices are weak and we're seeing that weigh on the market," said Peter Cardillo, chief market economist at First Standard Financial.
U.S. crude oil futures settled down $1.07, or 2.56 percent, at $40.67 a barrel, while brent held near $43.60 a barrel as focus returned to global oversupply.
Crude gained 2.45 percent Monday, boosted by geopolitical concerns following weekend terror attacks in Paris.
See CNBC's full Paris coverage here
"The market has come to realize that in the short term these are not hugely market-moving events. ... But the tragedy in Paris Friday has real political implications for not only the refugee crisis but also (German Chancellor Angela) Merkel's position in Germany and I don't think it's overstating that Merkel has been (crucial) to keeping Europe together," said David Lafferty, senior vice president and chief market strategist at Natixis Global Asset Management.
"The environment (trading) is occurring in I think is one in which investors are very confused," he said. "After the China selloff and the market rebound, the market has been directionless."
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In economic news, the consumer price index rose 0.2 percent in October, matching estimates. The so-called core CPI, which takes out food and energy costs, gained 0.2 percent. In the 12 months through October, core CPI increased 1.9 percent.
"I wouldn't call it a market-moving number but it showed continued progress in terms of what the Fed is looking for," Lafferty said.
Dow futures held about 60 points higher after briefly adding 100 points prior to the data release.
"I think the geopolitics is always going to be simmering in the backdrop. We came into the week pretty oversold, caught a bid yesterday and that's continuing today," said Art Hogan, chief market strategist at Wunderlich Securities.
"Retailers may have an opportunity to trade up with the halo effect," he said.
In other data reports, home builder confidence fell more than expected to 62 in November.
Industrial production for October showed a second-straight month of decline with a 0.2 percent drop, missing expectations for a slight rise.
Treasury yields came off session highs, with the 10-year yield near 2.27 percent and the 2-year around 0.86 percent in early afternoon trade.
The U.S. dollar held near 7-month highs, trading mildly higher against major world currencies, with the euro near $1.064 and the yen at 123.40 yen against the greenback in the close.
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European stocks surged Tuesday, with the STOXX Europe 600 up more than 2 percent, as markets found confidence from euro zone data.
Most major Asian indexes closed more than 1 percent higher Tuesday, with only the Shanghai composite ending a touch lower. The rally followed gains of more than 1 percent in U.S. stocks Monday on the sharp jump in oil prices.
"Improved intraday momentum has allowed for short-term oversold "buy" signals around the world (based on upturns in the daily stochastics)," BTIG Chief Technical Strategist Katie Stockton said in a morning note. "We think that the ability of global equity benchmarks to gap up in the face of geopolitical risk reveals the positive seasonal influences that are at hand."
Investors also eyed some speeches from Federal Reserve members ahead of Wednesday's release of the Fed meeting minutes.
Introducing central clearing to tri-party and bilateral repo trading could help reduce "fire sales" and liquidity risks, and add more transparency to sometimes murky U.S. markets, Fed Governor Jerome Powell said in a Reuters report.
Federal Reserve Governor Daniel Tarullo said in a Reuters article that the United States is in a "grace period" of lowered financial risk but should address the potential for increased problems to develop in the financial system's non-bank sector.
Former Fed Chairman Ben Bernanke is due to speak after the close.