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CNBC's Battle of the Beer Labels: Suds Sixteen announced

In the end, round two of the battle between Newburgh Brewing and White Lion Brewing turned out to be as heated as expected.

Both put up the second- and third-highest totals in the second round. While Springfield, Massachusetts-based White Lion gave it everything it had, Newburgh came out on top after a back-and-forth affair by a final of 1,936 to 1,851.

While Newburgh has to be feeling good after winning such a tight contest, there could be black clouds on the horizon — or you might say a Black Hog.

Last year's champ will now defend its title against Black Hog Brewing, which won its faceoff with fellow Connecticut brewer Two Roads Brewing. Black Hog has put up the most votes in each round and looks to be making itself the label to beat after two rounds.

What was the closest matchup in round two? Blue Moon Brewing's artist series label, which bested Arcadia Ales by 31 votes. It will face Cincinnati's MadTree Brewing for a spot in the Elite Eight.

Read MoreClick here to view a gallery of all the contestants

When the Suds Sixteen kicks off Monday, new entrant Tree House Brewing and its Juice Machine will square off against Relic Brewing's RyePocalypse.

Other notable matchups include perennial label powerhouse Deschutes versus Sierra Nevada, which has been putting up big numbers with its barrel-aged Narwhal label.

Other Suds Sixteen matchups that could come down to the wire based on this year's action so far: Dogfish Head's Tuxedo label taking on Jester King's Funk Metal; last year's runner-up Founders Brewing Azacca meeting Gigantic Brewing's Catch 23; and Odell Brewing's IPA versus Ninkasi Brewing's Ground Control.

A full list of round three matchups can be found here. Voting for the Suds Sixteen starts on March 21 at 1 p.m. ET.