It's been suggested that some of the most important developments in the coming days will be appointments to the new cabinet, which could signal a willingness to tackle governmental reform and ultimately help secure a new financing round from IMF.
"Arguably the most important question following Yatsenyuk's departure is whether Finance Minister Natalie Jaresko will remain in her position," Daragh McDowell, Principal Analyst, Europe and Central Asia at Verisk Maplecroft, told CNBC via email.
Rumours in recent months suggested Jarekso might be tapped to take over as prime minister, but those rumblings have since been quashed.
"Jaresko is one of the last genuinely reformist and technocratic ministers in the government, and we expect that her departure would be interpreted negatively by Ukraine's western partners," McDowell explained.
If Groysman is formally approved as prime minister by parliament, he could find it relatively easy to implement macro-economic reforms and back-track on "populist impulses" like gas price hikes introduced in recent weeks, Ash explained. However, anti-graft measures will be tougher to tackle, he said.
Poroshenko is already suffering a blow after being named in the Panama Papers for having set up an offshore firm in the British Virgin Islands in 2014 while the country was in the grips of a war with pro-Russian separatists in the country's eastern region.
Nonetheless, creditors might be willing to give Ukraine the benefit of the doubt amid a cabinet reshuffle, with a new tranche potentially signed off over the next one to two months, Ash suggested, but would require much stronger commitment to reforms by Poroshenko and his BPP party which has so far failed to deliver.
Otilia Dhand, Senior Vice President at Teneo Intelligence, said in a research note that tranche could total $1.7 billion. However, she was similarly pessimistic about the release of funding going forward.
"Going on Ukraine's previous record, with no real change in parliamentary dynamics and the less technocratic profile of the cabinet under Groysman, the benchmarks will be difficult to achieve, making further delays in funding likely," Dhand said.