As of early Wednesday, Trump had 61 percent of the GOP vote in Tuesday's primary to 25 percent for Ohio Gov. John Kasich and 12 percent to Texas Sen. Ted Cruz, according to NBC News. Clinton had 58 percent to Vermont Sen. Bernie Sanders' 42 percent.
In the race for 1,237 delegates needed for the Republican nomination, Trump has 844 to Cruz' 559 and Kasich's 146. Clinton's victory pushed her to 1,885 of the needed 2,383 Democratic delegates to Sanders' 1,190, NBC News said.
Trump delivered a confident victory speech, celebrating his success and discounting his rivals' chances.
"We're going to end at a very high level and get a lot more delegates than anybody projected, even in their wildest imagination," the real estate tycoon said at the top of his Tuesday evening victory speech to enthusiastic chants of "U.S.A."
Pointing out his fellow businessmen in the crowd of supporters, including billionaire Carl Icahn, Trump hit on some of his campaign's biggest promises.