"She is considerate and when you have someone who's considerate as she is, she makes a lot of common sense," Cramer said on "Squawk on the Street." "I know a lot of people criticize the Fed. I'm not going to if the Fed is Janet Yellen."
The Fed is widely expected to keep interest rates unchanged, and markets expect only a 2 percent chance of a rate hike Wednesday, according to the CME Group's FedWatch tool.
"Imagine if they tightened and you got that 38,000 employment number, you would say they don't really know what they're doing," Cramer said. "I think the empirical evidence proves that they do."
U.S. equities traded mildly higher ahead of the statement, with the three major averages up about 0.3 percent.