Wong, now 21, was unsuccessful in gaining admission to Smith, but she just graduated early from the University of Connecticut honors program as a stand-out poet and advocate for those who are transgender.
"This does not mean that I am in any way giving up on my cause," she said during her earlier media campaign. "I do this for the transfolk after me, so that they might inherit better policies and a more just system of education."
Smith, which had said Wong's paperwork didn't match her self-identified application, changed its policy in 2015. Now anyone who identifies as female may apply, regardless of their biological gender.
Nearby Mount Holyoke was one of the first to change its policy, in 2014.
"Being a woman is not static," college president Lynn Pasquerella told NBC News. "It's a social construct, just as race is a social construct."
Wong's case created a "sense of urgency to move quickly and make explicit our commitment to be as inclusive as possible while retaining our mission as a women's college," she added.
Since then, about 10 women a year are "actively transitioning," according to Pasquerella.
In addition to welcoming transgender women, the college supports biologically born women who may transition to male during their enrollment.
"Trans men also have a presence on campus and are fully embraced by our diverse student body," she said.
Because Mount Holyoke is part of a five-college system with other co-ed institutions, "it hasn't really changed the feel of the classroom," she said.
"We are not abandoning our mission," Pasquerella said. "We understand gender fluidity … It's complicated and we believe it's truly a human rights and civil rights issue."
Wong told NBC News she was unavailable for an interview, but a feature on her this year in UConn Magazine lauded her activism.
Wong, who majored in English and pre-med, said she wants to be a "culturally competent" endocrinologist working with patients with hormonal disorders and those who are transgender.
"I am many other things besides trans," she told the magazine. "I have a lot of room to grow. As people grow they become more things. It's our job as people to integrate these parts and to give other people the potential to integrate, too. We have a lot to learn from one another."