The social media company will use live tweets to enhance coverage of the presidential nomination process, on top of CBS News' digital streaming news service, CBSN, the companies said Monday.
The deal builds on previous partnerships from CBS' debate coverage over the past year. It comes as Twitter has upped its bets on live event videos, agreeing to stream Thursday night NFL games this fall.
Both Twitter and CBS are at a crucial point as they seek to monetize their content.
Shares of Twitter, down about 48 percent over the past 12 months, have been under pressure as user growth and engagement have been "challenged," according to analysts at SunTrust, who downgraded the stock on Monday. Meanwhile, CBS is spinning off its radio unit, which filed for IPO last week.
Both the Democrats and Republicans have said they planned to leverage technology to expand the experience of the conventions.
"Twitter is the fastest way to find out what's happening in politics and to have a discussion about it," Twitter Chief Financial Officer Anthony Noto said in a statement. "We believe we're giving people around the world the best way to experience democracy in action."