Facebook's stock surged more than 3 percent Thursday, the morning after the company posted earnings and revenue that blew past analyst estimates. Shares jumped nearly 6 percent Wednesday after hours, briefly over $131 per share.
"[Zuckerberg] made a case that said look, there is going to be 7 billion people. ... We are going to wire the world," Cramer told CNBC's "Squawk on the Street." "The natural way to communicate is through video. He is basically saying, listen, virtual is now. Obviously the advertisers love it."
Cramer also noted Zuckerberg's talk with investors on the importance of artificial intelligence in the near future to serve consumers.
"What [Zuckerberg] is saying is people like to do many things at once," he said. "This is a very millennial thing. I pick up the phone ... 'Can I have reservations for two?' What he is basically saying is, I want to do that while I'm doing five other different things."
Separately, he adds comments on Facebook's strategy for advertisements and potentially "shorting" other competition. Facebook will take 67.9 percent of social-media advertising dollars worldwide this year, eMarketer estimates.
"Facebook does not have a lot advertisement yet versus what it is going to have," Cramer said.