And based on the data he's collected, Gates concludes that people with three backgrounds will be the most in-demand from here on out: science, engineering and economics.
Workers proficient in those subjects will be "the agents of change for all institutions," Gates tells LinkedIn Executive Editor Daniel Roth.
"I do think of basic knowledge of the sciences, math skills, economics — a lot of careers in the future will be very demanding on those things," Gates says.
You don't have to be an expert in coding or the periodic table, but having the ability to think the way these experts do will help you tremendously.
"[It's] not necessarily that you'll be writing code, but you need to understand what can engineers do and what can they not do," the Microsoft co-founder says.
They'll likely be revolutionizing your industry, he says.
If you're interested in picking up one of Gates' favorite books, check out his list of top reads from 2016.