Trump is expected to sign an executive order as early as Monday that will put in motion the renegotiation of the North America Free Trade Agreement (NAFTA).
President Trump is also expected to sign an executive order announcing his intention to withdraw from the Trans-Pacific Partnership (TPP), a trade agreement among 11 other Pacific Rim countries.
There are no major U.S. economic data reports scheduled to be released on Monday.
In Europe, the pan-European Stoxx-600 index was around 0.4 percent lower on Monday. In Asia, the Shanghai Composite in China closed 0.43 percent higher, while the Nikkei in Japan closed 1.29 percent lower.
In oil markets, prices eased on Monday as the likelihood of rising U.S. production weighed on the market. Energy companies in the U.S. added the most rigs drilling for new production in nearly four years.