An indictment against Manafort and an aide on money laundering and tax evasion charges was unsealed Monday.
Podesta, a Democratic lobbyist whose brother John was Hillary Clinton's presidential campaign chairman, announced his decision to step down during a company meeting on Monday morning, Politico reported. He will give full operational and financial controls to CEO Kimberley Fritts, according to Politico.
Fritts and a senior group of people will launch a new firm within the coming days, Politico reported, noting that sources said the transition has been in the works for the past several months.
Neither Tony Podesta nor The Podesta Group immediately responded to CNBC's requests for comment.