Trump will be examined by the same doctor as predecessor Barack Obama, the report said, and a summary of the results is expected to be made public. The routine physical was first announced by the White House late last year.
The customary examination will reportedly last around two hours and is set to include blood and urine tests, heart checks and questions about Trump's sleeping habits and sex life. Nonetheless, Trump has the power to hold back any details he wishes.
The formal medical check will be Trump's first since entering the White House and comes at a time of intense speculation about his mental and physical suitability for the presidency. Last week, an explosive book by journalist Michael Wolff alleged Trump would frequently fail to recognize old friends and often repeated stories "word for word." The president described the book as "fiction" and claimed he was a "very stable genius."