* Automakers spend heavily to adapt factories
* Investors see net sales boost for parts makers from EV
* Some go higher up supply chain to lithium, hydrogen tech
LONDON, March 7 (Reuters) - As carmakers ramp up spending on self-driving and electric vehicles (EVs), many investors are betting their component suppliers will be the first winners from the technology shifts.
Asked how they are positioning for the changes, investors interviewed by Reuters more often mentioned suppliers like Aptiv , Valeo and Continental than the big car brands building them such as Volkswagen, Daimler and Peugeot.
That partly reflects a long-term shift towards more complex vehicles where components makers are contributing an ever-larger proportion of a car's total value.
It is also an acknowledgement that the big innovations are happening as much in the auto industry's scattered supply base as in the design hubs of the big carmakers, also known as original equipment manufacturers (OEMs).
"We ... feel the structural growth opportunities and visibility in the suppliers is higher than for the OEMs where more uncertainties exist, debt is higher and margins/returns typically lower," said Marcus Morris-Eyton, European equities portfolio manager at Allianz GI.
His Allianz Continental European fund's main exposure to the EV trend is through German semiconductor maker Infineon , which represents 4.1 percent of the fund, along with tyres and parts supplier Continental.
Thomas Fitzgerald, associate fund manager at EdenTree Investment Management, also holds Infineon stock as an EV/autonomous cars play, as well as Swedish car safety equipment maker Autoliv and Aptiv, the former Delphi businesses now focused on networked EV architecture.
"Those companies providing technology which supports an autonomous, connected, shared and electric transportation system are well positioned to experience heightened levels of profitable growth over the long term," said Fitzgerald.
While a European index of auto stocks is down 1.3 percent this year, that is less than the broader STOXX 600's 5.1 percent drop and places it among the top-performing European sectors so far in 2018.
For carmakers, the shift to EVs carries huge costs and risks, with many slashing billions from their cost base to help offset the lower profitability of electric cars.
Even premium manufacturers with the highest profit margins are bracing for some pain. Daimler says it will face a significantly lower margin "in the beginning of the cycle".
With governments stepping up efforts to reduce pollution, carmakers plan to plough at least $90 billion globally into EVs, according to a Reuters analysis.
Much of this has been driven by strict quotas that China, the world's largest auto market, has set for new-energy vehicles (NEVs) and which are coming into force in 2019.
"We have strongly increased our exposure to this theme as we now believe that EVs are in a position to become competitive in less than five years," said Lyxor Asset Management's head of global equities, Fabrice Theveneau.
He expects parts makers to sell more products to OEMs, which he believes will be "net losers" from the EV shift, losing market share to new competitors such as Tesla and facing heavy costs to transform their industrial base.
Some investors are wary of the high valuation of many EV-related tech stocks - Infineon rose 38 percent and STMicroelectronics 69 percent last year - before mass adoption has even begun.
Lyxor's Theveneau instead favours tyremakers Continental, Pirelli and Michelin as he expects demand for premium tyres to pick up as the average EV will drive further than a conventional car.
He also owns shares in battery material miners Glencore , Eramet and Covestro as well as industrial gas makers Linde and Air Liquide -- both plays that offer him an option on the success of hydrogen cars, a rival technology to EV.
Theveneau still has carmakers Renault, Nissan and Toyota among his top picks. "It's a race: some of the market shares will change, you don't know who is going to win in the end."
Wesley Lebeau, who manages a disruption-themed fund at Amundi's CPR Asset Management, is also looking along the EV supply chain. Umicore is one of his top 10 holdings thanks to its dominant position in cathode materials used in automotive batteries. Lebeau also has exposure to lithium miners SQM in Chile and Orocobre in Australia.
Gavin Launder, senior portfolio manager in the active equities team at Legal & General Investment Management, is staying positive on the German automakers in particular, saying they will aim to claw back market share in premium EVs from electric car trailblazer Tesla.
He says the German car manufacturers tend to be better funded than rivals and have spent more on research and development over the years.
He holds a position in Daimler, which last month unveiled a new Mercedes-Benz A-Class with its own machine-learning and voice recognition technology.
"I'm pretty convinced that when Mercedes starts launching electric vehicles that look like Mercedes, that feel like Mercedes, they will have a decent place in the market," he said.
(Additional reporting by Tom Pfeiffer Editing by Tom Pfeiffer and Mark Potter)