Among Mexican President Andres Manuel Lopez Obrador, Powell and Xi, Cramer said Trump suggests, by his words, that he believes "Powell is probably the worst for the country" and "Powell is not a friend."
Trump on CNBC on Monday criticized the Fed for raising interest rates too quickly, calling the four hikes last year "very, very disruptive."
"It's more than just Jay Powell. We have people on the Fed that really weren't — they're not my people. But they certainly didn't listen to me because they made a big mistake: They raised interest rates far too fast," Trump told CNBC's Joe Kernen on "Squawk Box."
The president also blasted central bankers for their balance-sheet runoff program, which allows bonds in the Fed's portfolio to mature without replacing them. The balance sheet had swelled to more than $4.5 trillion in early 2015 in the wake of several rounds of quantitative easing, or bond-buying, aimed at boosting the economy after the 2008 financial crisis.
The Fed — responding to CNBC's request for reaction to the Cramer and Trump remarks — said it had no comment.
Trump has widely and repeatedly criticized Powell, even reportedly discussed firing the Fed chairman, whom he actually appointed. Powell responded in January to the reports, saying he would not resign if Trump were to ask.