100 of the world's most promising start-ups to watch in 2019

Every year, CNBC scans the globe looking for the 100 venture-backed start-ups that have the potential to transform industries and become tomorrow's household names. Our 2019 Upstart 100 list showcases young start-ups that are building and scaling businesses addressing the rapidly changing technological era we live in. Selected from more than 600 nominees globally, each one was scored on eight equally weighted quantitative metrics (read more about our methodology here).

Each Upstart has raised no more than $50 million in venture capital, which means valuations are still relatively low, while promise and potential are high. And although the unicorns of 2019 have represented at times frothy, fadlike market trends, the Upstart 100 companies present a broader picture of where venture capitalists are placing their bets in the more distant future.

The companies that made this year's Upstart 100 list represent nearly every sector of the economy, from enterprise software and finance to insurance, health care and retail. They come from 10 different countries, 16 U.S. states and DC. Of the 100, 25 are led by women. All of them are less than five years old, but 40 are less than three years old and 11 were founded just last year.

And all of the 100 companies on the list have quickly become entrepreneurial success stories worth keeping an eye on.

Upstart 100 2019

Company Description Headquarters Founded
AiFiAI-driven checkout-free systems for retail storesSanta Clara, CA2016
Airspace TechnologiesLogistics platform for time-sensitive shipments, like donated organs or replacement partsSan Diego2019
AISERAAI-driven help desk for IT, HR and customer servicePalo Alto, CA2017
Alpha MedicalMobile platform providing basic health-care services for womenPalo Alto, CA2017
AporetoCybersecurity solution for hybrid and multicloud workplace applicationsSan Jose, CA2016
Arkose LabsFraud and abuse prevention for large enterprises, backed by PayPalSan Francisco2017
ArrcusFlexible operating system for enterprises, deployable in data centers and on the cloudSan Jose, CA2016
AttaboticsRobotic supply chain system that reduces warehouse space needsCalgary, Alberta, Canada2016
Awake SecurityAutomated cyberthreat detection and triageSanta Clara, CA2014
AxoniusCybersecurity for a company's myriad connected devicesNew York2017
BeddrFDA-cleared sleep-monitoring appMountain View, CA2017
Beekeepers NaturalsHealth and wellness products made from honey and honey byproductsLos Angeles2015
BloomscapeE-commerce houseplantsDetroit2018
Blue HexagonDeep-learning cybersecurity platform founded by a former Qualcomm engineerSunnyvale, CA2017
BookDocAppointment booker and online health-care platformSelangor, Malaysia2015
brrr°Maker of cooling fabrics for apparel brands like Gap and Jos. A. BankAtlanta2015
CHEQAI-driven ad verification that exposes fake fansTel Aviv, Israel2016