The New York-based airline said this will entail offsetting between 15 billion and 17 billion additional pounds of emissions per year, which the company noted is "the annual equivalent of removing more than 1.5 million passenger vehicles from the road."
The airline will offset the carbon impact of its jet fuel by investing in projects focused on forest conservation and landfill gas capture, as well as in solar and wind power generation initiatives.
The company also said that it will begin using sustainable aviation fuel this year, purchased from Finland-based Neste, on flights from San Francisco International Airport.
The plan is an extension of initiatives already in place, which have seen JetBlue purchase more than 2.6 billion pounds of carbon dioxide offsets since 2008, according to the company's website.
The airline did not say how much the proposed plan will cost, and did not mention any plans for offsetting international flights. In addition to the United States, the company currently operates in the Caribbean, Central America and parts of South America, and is in expanding to Europe.
JetBlue is not the first airline to outline plans for becoming carbon neutral — in November, United Kingdom-based EasyJet began offsetting carbon emissions — but it is the first U.S.-based airline to target becoming carbon neutral. Other airlines, however, do have carbon offsetting programs, including Delta and United.
The announcement comes as consumers are increasingly focused on the environmental impact of flying. A movement known as "flight shaming" has gained traction, and Swedish climate activist Greta Thunberg in August took a widely-followed boat ride across the Atlantic due to the high carbon impact of flying.
- CNBC's Leslie Josephs contributed reporting.