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* Shares of airlines, cruise lines lead declines
* Bank stocks track a fall in U.S. Treasury yields
* Tech firms ask Seattle employees to work from home
* Indexes down: Dow 3.73%, S&P 3.66%, Nasdaq 3.19% (Updates to mid afternoon)
March 5 (Reuters) - U.S. stocks sold off sharply on Thursday, with shares of travel companies pummeled, as large swings in the market continued amid uncertainty over the spread of the coronavirus and its economic fallout.
The major indexes were down over 3% a day after they tallied huge gains following moderate Joe Biden's success in the Super Tuesday primaries for the Democratic presidential nomination.
Declines resumed along with continued volatility as investors grappled with the ultimate economic impact from the coronavirus, which has led to more than 3,300 deaths worldwide.
In the latest developments, Alphabet Inc's Google joined other big tech firms in recommending employees in the Seattle area to work from home, while new cases arose around New York and Los Angeles.
Theres no way to put a framework around this, theres no way to model it, because you just dont know," Carol Schleif, deputy chief investment officer, at Abbot Downing in Minneapolis.
"The market is clearly trading on emotion today and not fundamentals because they cant peg where the fundamentals are, Schleif said.
The Dow Jones Industrial Average fell 1,010.46 points, or 3.73%, to 26,080.4, the S&P 500 lost 114.57 points, or 3.66%, to 3,015.55 and the Nasdaq Composite dropped 288.07 points, or 3.19%, to 8,730.02.
The benchmark S&P 500 was last down over 10% from its Feb. 19 closing high.
The financial sector dropped 5.3% as the continued fall in Treasury yields weighed on rate-sensitive bank shares, with the yield on the 10-year Treasury note falling to 0.92%. Defensive sectors, such as utilities and consumer staples, were down less than the overall market.
The CBOE Volatility index, Wall Street's fear gauge, jumped 8.63 points to 40.62.
Shares of companies in the travel and leisure industry were punished, with the S&P 500 airline index off 7.1%, including a 10.3% fall for American Airlines Group Inc.
The coronavirus epidemic could rob passenger airlines of up to $113 billion in revenue this year, an industry body warned.
Shares of cruise operators tumbled after the Grand Princess ocean liner, owned by Carnival Corp, was barred from returning to its home port of San Francisco on coronavirus fears after at least 20 people aboard fell ill. Carnival shares dropped 13.7%, while Royal Caribbean Cruises fell 15.5%.
Data showed that the number of Americans filing for unemployment benefits fell last week, suggesting the labor market was on solid footing despite the coronavirus outbreak, with investors casting an eye toward Friday's U.S. employment report for February.
Declining issues outnumbered advancing ones on the NYSE by a 6.38-to-1 ratio; on Nasdaq, a 4.96-to-1 ratio favored decliners.
The S&P 500 posted 8 new 52-week highs and 73 new lows; the Nasdaq Composite recorded 25 new highs and 282 new lows. (Additional reporting by Medha Singh and Sanjana Shivdas in Bengaluru; Editing by Arun Koyyur and Nick Zieminski)