Dozens of people were reportedly killed and injured after an airstrike on the Jabalia refugee camp in northern Gaza on Tuesday.
The Hamas-run health ministry, and the director of the nearby Indonesian hospital, said that at least 50 people had been killed in the blast. CNBC was unable to independently verify the number of casualties.
An IDF spokesperson said the Israeli military killed senior Hamas commander Ibrahim Biari, one of the architects of the Oct. 7 terror attack, during the deadly strike. CNBC was not able to confirm his death.
Clashes between Israeli forces and Hamas escalated in the northwest of the Gaza Strip on Tuesday, according to an outlet affiliated with the Palestinian militant group.
Al-Qassam Brigades, the armed wing of Hamas, fired anti-tank missiles on Israel's forces early morning, Gaza Now said on social media, with two tanks and bulldozers targeted.
Separately, Israel's Defense Forces said it had struck 300 Hamas targets in ground operations over the past day. Anti-tank missile posts, rocket launch posts and underground compounds were hit, the IDF said.
"There are ground units of the [Israel Defense Forces] that are expanding the activity in northern Gaza, we're operating there with what we call joint combat teams, on the ground, joint in the sense of ground forces, air and sea cooperating together, seeking to establish contact with the enemy, engage with him, and then use our capabilities to strike the enemy," IDF spokesperson Jonathan Conricus told MSNBC in a TV interview.
CNBC could not independently verify reports from the ground.
It comes after Israeli Prime Minister Benjamin Netanyahu told reporters Monday that he would not agree to a cease-fire with Hamas, saying it would be tantamount to a surrender" to the militant group.
He also said Hamas was responsible for the high death toll in Gaza, accusing it of using civilians as human shields.