CNBC's Jim Cramer on Thursday sought answers from Rite Aid after the retailer cut its full-year profit forecast for a second time this year and lowered the top end of its sales forecast.

Pedestrians walk past a Rite Aid store in Oakland, Calif.

"They blew up the quarter, but the guidance is horrendous. It's horrendous," Cramer said on "Squawk on the Street." "They lost exclusivity on certain drugs that were generic, but you know what, that's not good enough" of an explanation.