Three major U.S. tobacco companies including R.J. Reynolds Tobacco, Lorillard, and Altria's Philip Morris USA will pay $100 million to settle hundreds of federal lawsuits over smoking, according to an announcement from plaintiffs' lawyers on Wednesday.

The agreement will cover more than 400 lawsuits filed in federal court in Florida by smokers or their families, according to the announcement. The settlement will not cover cases that have gone to trial or already reached a verdict.