U.S. stock index futures indicated a lower open on Thursday as traders looked to a speech on inflation and policy from U.S. Federal Reserve Chair Janet Yellen, one week after the central bank surprised the markets and helped stir up new fears of deflation.

In morning economic news, durable goods showed a decline of 2 percent. Weekly jobless claims came in at 267,000. New home sales will be released at 10:00 am, ET.