Donald Trump's trade plan would hurt American businesses and workers, Hewlett Packard Enterprise CEO Meg Whitman told CNBC on Wednesday.

"I think his policies around free trade will be damaging to businesses as a whole," said Whitman, a Republican who waged an unsuccessful gubernatorial campaign in California in 2010. "We have to be the most cost-effective competitor in the world. We've got to compete against Huawei, against Lenovo, … so, we've got to be incredibly cost effective."