Debt-cutting measures need to be a consideration for President-elect Donald Trump, as he prepares to execute on campaign promises to boost infrastructure spending, rebuild the military and slash taxes, according to the bipartisan co-chairs of the Campaign to Fix the Debt.

Trump policies, without red ink-reducing components, "[by] our estimate would explode the debt by $5 trillion in the first 10 years ... and by the end of 10 years our debt as percentage of GDP would be over 100 percent," Democratic former Pennsylvania Gov. Ed Rendell told CNBC's "Squawk Box" on Tuesday.