The Dow Jones Industrial Average posted its biggest loss since 2020 on Wednesday after another major retailer warned of rising cost pressures, confirming investors' worst fears over rising inflation and rekindling the brutal 2022 sell-off.

The Dow shed 1,164.52 points, or 3.57%, to 31,490.07, the average's biggest decline since June 2020. It was the lowest close for the Dow since March 2021.