This photo provided by the Missouri State Highway Patrol and taken with a drone as it surveys the damage from a tornado that hit southeast Missouri early Wednesday, April 5, 2023. The tornado caused widespread destruction and killed and injured multiple people.

A "significant" tornado tore through southeastern Missouri on Wednesday morning, killing multiple people and leaving widespread destruction as authorities warned of more twisters.

The Missouri State Highway Patrol sent troopers to Bollinger County to assist "multiple local agencies in search and recovery efforts after a tornado" in the Glen Allen area, the agency said in a statement.