This was CNBC's live blog tracking developments in the Israel-Hamas war. Click here for the latest Israel news and updates on Gaza.
Hospitals in Gaza have warned that they would need to shut down if they don't receive more fuel. Other supplies — such as water, medicine and food — also continue to run low.
The United Nations Relief and Works Agency for Palestine Refugees previously noted it would be unable to carry out aid operations after Wednesday night if it does not receive fuel supplies necessary for transport, water desalination and running medical equipment. The Israel Defense Forces insist that fuel is present in Gaza but that Hamas is monopolizing it.
The Biden administration is now backing the idea of a "pause" in Israel's military operations against Hamas in order to allow more aid to get into Gaza, NBC News reported.
U.N. Secretary-General António Guterres warned overnight that the situation is "growing more dire by the hour" in the Middle East and urged respect for civilian lives as the conflict unfolds.
Israel's representative to the U.N. has called for the resignation of Guterres, following his remarks on the Israel-Hamas conflict and action in Gaza.
In response, Guterres said he was "shocked by the misinterpretations" of his address made before the U.N. Security Council.
In a televised address, Israel Prime Minister Benjamin Netanyahu again said that Israel is preparing for a ground invasion of Gaza but provided no other details about timing.
U.S. President Joe Biden reiterated that the U.S. is working to secure the release of all hostages being held by Hamas. Speaking at the White House, he also said there must be a "two-state solution" to the conflict in Israel and Gaza.
The Israel Defense Forces said it carried out an operation in northern Gaza overnight, in which tanks and infantry targeted "numerous terrorist cells, infrastructure and anti-tank missile launch posts."
The military said its troops have since exited the area and returned to Israeli territory.
"Overnight, the IDF conducted a targeted raid using tanks in the northern Gaza Strip, as part of preparations for the next stages of combat. The activity was commanded by the Givati Brigade," the IDF said in a statement.
— Christine Wang
Oxfam released a statement saying "just 2 percent of usual food has been delivered to Gaza" since the siege was imposed.
" The international agency analyzed UN data and found that just 2 percent of food that would have been delivered has entered Gaza since the total siege - which tightened the existing blockade - was imposed on 9 October," Oxfam said.
The agency renewed its call for food, water, fuel and other essentials to be allowed to enter.
"The situation is nothing short of horrific - where is humanity?" Oxfam spokesperson Sally Abi Khalil said in a statement. "Millions of civilians are being collectively punished in full view of the world, there can be no justification for using starvation as a weapon of war. World leaders cannot continue to sit back and watch, they have an obligation to act and to act now. "
Oxfam estimates a staggering 2.2 million people are now in urgent need of food.
— Riya Bhattacharjee
The Biden administration is now backing the idea of a "pause" in Israel's military operations against Hamas in order to allow more aid to get into Gaza as the international community sounds the alarm on a growing humanitarian crisis in the region, NBC News reported.
Biden stressed the need for more aid into Gaza at a news conference with Australian Prime Minister Anthony Albanese, saying that Israel needed to do "everything in its power to protect innocent civilians."
A U.S. official told NBC News the shift in the administration's language was deliberate.
The official also said that the Israelis are "hearing" the call for a humanitarian pause and it is "actively being discussed."
Read the full story on NBC News.
— Riya Bhattacharjee
Some White House aides have worried that President Joe Biden's response to the ongoing Israel-Hamas conflict has not shown enough empathy for Palestinian civilians as well as the U.S. Muslim community, sources told NBC News.
Administration officials have been seeking out Muslim officials and advocates to talk about issues affecting their communities and help the White House address those matters, NBC reported.
Biden's comments and actions will continue to be scrutinized as the death toll rises in Gaza.
Read the full story here.
— Amanda Macias
A senior Treasury official met with counterparts in Qatar to discuss ways to cut Hamas' funding stream.
"The U.S. is prepared to take unilateral action, but when we are strategically aligned with partners in this region, we have a great chance for success at a greater speed with more efficiency," said Brian Nelson, Treasury's under secretary for terrorism and financial intelligence.
Nelson hinted that the department will extend the offer to other countries in the Middle East and said he spoke with officials in Saudi Arabia on Tuesday.
Prompted by the Hamas attacks, the Treasury's Office of Foreign Assets Control last week sanctioned 10 institutions that fund Hamas from Gaza, the West Bank, Sudan, Turkey, Algeria and Qatar.
The terrorist group is funded in part through charitable organizations — including Turkey's IHH Humanitarian Relief Foundation — taxes on Gazan-made goods and imports and provisions from Iran.
— Chelsey Cox
U.S. Agency for International Development Administrator Samantha Power spoke to representatives of the U.N.'s Office of Coordination of Humanitarian Affairs to discuss "unhindered humanitarian access" for civilians in Gaza.
Power also called "for the protection of civilians in accordance with international humanitarian law" according to a USAID statement.
"Administrator Power reaffirmed the United States' commitment to support those impacted by the ongoing conflict," the statement added.
— Amanda Macias
The State Department said Assistant Secretary of State for Near Eastern Affairs Ambassador Barbara Leaf is on her way to meet regional partners to discuss ways to mitigate the ongoing Israel-Hamas conflict from spreading across additional borders.
"She will discuss humanitarian solutions to protect civilians while reiterating U.S. support for a region that advances the aspirations of all its people," the State Department wrote in a statement.
The State Department said that Leaf will begin in the United Arab Emirates before traveling to Qatar, Oman, Egypt, Jordan and then Israel. The State Department said that Leaf may make additional stops but declined to elaborate.
Leaf's trip comes on the heels of high-level visits made by President Joe Biden and Secretary of Defense Lloyd Austin to Israel and a multi-country tour by Secretary of State Antony Blinken.
— Amanda Macias
The Pentagon is working to provide Israel with additional Iron Dome support, a Defense official confirmed to NBC News.
"As we've said previously, the U.S. will be flowing additional Iron Dome support to Israel," added the official, who spoke on the condition of anonymity. "As a result, the Department of Defense is currently engaged in planning to support the provision of U.S. Iron Dome batteries to Israel," the official added.
Read more about the Iron Dome here.
— Amanda Macias
Australian Prime Minister Anthony Albanese said he discussed the ongoing war with President Joe Biden during their bilateral meeting.
"Last night and again today we spoke about the situation in Israel and Gaza. Australia unequivocally condemns the terrorism of Hamas. We grieve for the loss of every innocent life, whether they be Israeli or Palestinian. In times of crisis, respectful international humanitarian law is paramount," Albanese said during a press conference alongside Biden at the White House.
Albanese said the two also discussed Russia's full-scale invasion of Ukraine, and Biden welcomed the announcement of additional military assistance for Ukraine.
Albanese also announced that Australia will give an additional $15 million in humanitarian aid to civilians in Gaza, adding to the $10 million it has already committed.
— Amanda Macias
President Joe Biden said his administration is working with regional partners to secure the release of all the hostages being held by Hamas.
"We're also working around the clock together with our partners in the region to secure the release of hostages," Biden told reporters at the White House.
Biden said the U.S. is also working on the safe passage of foreign nationals who are trapped in Gaza.
"Not just Americans but Australians and a whole range of people are trapped in Gaza," Biden said, alongside Australian Prime Minister Anthony Albanese.
— Amanda Macias
President Joe Biden expressed concern about extremist settlers attacking Palestinians as tensions in the Middle East soar.
"I continue to be alarmed about extremist settlers attacking Palestinians and the West Bank. That is like pouring gasoline on fire," Biden said during a press conference at the White House.
"They're attacking Palestinians in places that they're entitled to be. It has to stop. They have to be held accountable and it has to stop now," he added.
— Amanda Macias
Editor's note: The following post contains a photograph with graphic content.
The family of Al Jazeera Gaza bureau chief Wael Al-Dahdouh has been killed in an air strike in Gaza, Al Jazeera reported.
Al-Dahdouh's wife, son and daughter were killed in the strike, he told Al Jazeera. Images on Al Jazeera show him entering a hospital in Gaza to view their bodies.
Al-Dahdouh had sent his family to the Nuseirat refugee camp south of Wadi Gaza.
Details of the strikes are still coming in.
— Riya Bhattacharjee
President Joe Biden on Wednesday stressed that there must be a "two-state solution" to the conflict in Israel and Gaza.
"There's no going back to the status quo as it stood on Oct. 6. That means Hamas can no longer terrorize Israel and use Palestinians as human shields," Biden said, speaking outside the White House. "It also means, when this crisis is over, there has to be a vision of what comes next, and, in our view, it has to be a two-state solution."
The president also implored Israel to abide by the rules of war and "do everything in its power … to protect innocent civilians."
"Hamas does not represent the vast majority of the Palestinian people in the Gaza Strip or anywhere else," Biden added. "Hamas is hiding behind Palestinian civilians and it is despicable and, not surprisingly, cowardly.
"This also puts an added burden on Israel while they go after Hamas, but that does not lessen the need to operate and align with the laws of war," Biden said. "Israel has to do everything in its power, as difficult as it is, to protect the lives of innocent civilians."
— Emma Kinery
Boeing said the the Israel-Hamas war could impact some of its suppliers.
"The current conflict in Israel and the Gaza Strip has the potential to impact certain of our suppliers, and has already impacted some operations for our airline and lessor customers," Boeing said in a quarterly filing, after reporting a third-quarter loss. "We are closely monitoring developments, supporting our employees and customers, and will take mitigating actions as appropriate."
The aircraft manufacturer and defense contractor relies on a sprawling global supply chain, which is already under stress coming out of the pandemic. Boeing didn't immediately provide more details on which of its suppliers could be impacted.
— Leslie Josephs
Israel Prime Minister Benjamin Netanyahu said today that it had "eliminated thousands of terrorists" in the ongoing conflict between Israel and Hamas in Gaza.
"We're bringing hellfire on Hamas, we've eliminated thousands of terrorists," he said, addressing the nation this evening.
He said that Israel has two goals in the war, "toppling Hamas and bringing our captives home."
He said Israel was "working around the clock to actualize the targets of the war" and was focused on "saving the country and bringing victory."
He also said he would establish national days of mourning.
Editor's note: A previous version of this post contained a quote that was unclear in translation. CNBC has deleted that quote.
Israel is preparing a ground invasion of Gaza, Prime Minister Benjamin Netanyahu said in a televised statement on Wednesday, but he declined to provide any details on the timing or other information about the operation.
He said the decision on when forces would go into the blockaded Palestinian enclave would be taken by the government's special war cabinet.
—Reuters
Israel on Wednesday pushed back against Turkish President Recep Tayyip Erdogan's assertion that the Palestinian militant group Hamas was not a terrorist organization.
"Israel wholeheartedly rejects the Turkish president's harsh words about the terrorist organization Hamas," Foreign Ministry spokesperson Lior Haiat wrote in a post on social media.
"Even the Turkish president's attempt to defend the terrorist organization and his inciting words will not change the horrors that the whole world has seen," he added.
Erdogan said earlier Wednesday that "Hamas is not a terrorist organization" and stressed that he would not be carrying out a planned visit to Israel amid the country's ongoing campaign in the Gaza Strip.
— Karen Gilchrist
The Senate Foreign Relations Committee voted 12-9 to move former Treasury Secretary Jack Lew's nomination to be the next ambassador to Israel to the full Senate.
Republican Senator Rand Paul of Kentucky was the only Republican vote that joined all the 11 Democrats on the committee.
Lew's nomination now goes to the Senate floor, where a final confirmation vote is expected for next week.
— Amanda Macias
United Nations Secretary-General Antonio Guterres on Wednesday hit back at claims that he had justified Hamas attacks on Israel, calling them a misrepresentation.
On Tuesday, Guterres told the U.N. Security Council in New York that "clear violations of international law" had been committed in Gaza and said it was important to recognize that Hamas' Oct. 7 attacks "did not happen in a vacuum."
The comments prompted outrage from Israel, with Israel's representative to the U.N. subsequently calling for Guterres' resignation.
Speaking to reporters Wednesday, Guterres said he was shocked by the backlash he had received.
"I am shocked by the misrepresentations by some of my statement ... as if I was justifying acts of terror by Hamas. This is false. It was the opposite," he said.
"I believe it's necessary to set the record straight — especially out of respect for the victims and their families."
— Karen Gilchrist
U.S. Democratic Sen. Joe Manchin said he would support former Treasury Secretary Jack Lew to be President Joe Biden's next ambassador to Israel. Lew was nominated last month by Biden.
"I look forward to supporting Jack's nomination for Ambassador to Israel, and it's essential that the Senate act on his nomination quickly so he can go to Israel and get to work immediately," Manchin wrote in a statement, calling Lew an "honest and straightforward person."
With Manchin's support, Lew is expected to win Senate confirmation.
Last week, Senate Foreign Relations Committee Chairman Ben Cardin (D-Md.) said the Senate could vote on Lew's nomination as soon as this week.
— Amanda Macias