Pops & Drops: Amylin, BHP Billiton...

Following are the day’s biggest winners and losers. Find out why shares of Amylin and BHP Billiton popped while General Motors and Advanced Micro Devices dropped.

POPS (stocks that jumped higher)

Amylin Pharmaceuticals (AMLN) popped 4%. An experimental once-a-week version of its diabetes drug, Byetta produced positive results. - Sooner or later I think this company gets attractive to Lilly, speculates Pete Najarian.

BHP Billiton (BHP) popped 4%. Japan’s TEPCO agreed to renew a natural gas contract with the company. - I don't think it's a great ride from here, muses Tim Seymour.

Textron (TXT) popped 4%. The industrial made more production cuts at its Cessna aircraft unit and it affirmed the company’s cash flow. - I think it's a little toxic here, says Guy Adami.

Prologis (PLD) popped 24%. Investors seem to believe that the REIT has been unfairly punished. - Jeff Macke doesn't know what to say.

ArcelorMittal (MT) popped 6%. Bank of America resumed coverage on this stock with a ‘buy’ rating. - I think you can take a shot but don't rush in, says Tim Seymour.

Charles Schwab (SCHW) popped 7%. The stock was among the many gainers in financials; the sector that led the market higher. - I think it's probably time to take profits, says Guy Adami.

Silver Wheaton (SLW) popped 4%. RBC Capital said the company should outperform its peer group. - You know how I feel about the miners, bristles Jeff Macke.

Autodesk (ADSK) popped 10%. UBS upgraded the maker of design software to “neutral” from “sell”.

DROPS (stocks that slid lower)

General Motors (GM) dropped 28%. The automaker was a top drag on the Dow due to concerns over the company’s sustainability. - Misty water-colored memories, says Jeff Macke sarcastically.

Advanced Micro Devices (AMD) dropped 4%. Rival Intel released a much-anticipated chip for server systems. - The drop is only 14 cents, reminds Pete Najarian.

International Paper (IP) dropped 5%. Investors bid the stock lower ahead of earnings out Thursday.

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Trader disclosure: On Mar. 31st, 2009, the following stocks and commodities mentioned or intended to be mentioned on CNBC’s Fast Money were owned by the Fast Money traders; Macke Owns (GS), (SDS), (AAPL), (POT), (MOS), (SDS); Macke Is Short (BRK.s); Adami Owns (AGU), (C), (GS), (INTC), (MSFT), (NUE), (BTU); Seymour Owns (AAPL), (BAC), (FXI), (FCX), (TSO), (EEM), (TTM), (WBD); Najarian Owns (AAPL) Call Spread; Najarian Owns (BNI) Call Spread; Najarian Owns (HUM) Call Spread; Najarian Owns (MS) Call Spread; Najarian Owns (NTRS) Call Spread; Najarian Owns (PALM) & (PALM) Calls; Najarian Owns (POT) Call Spread; Najarian Owns (XHB) Call Spread; Najarian Owns (RIO) Calls; Najarian Owns (VCLK) Calls