It looked like investors were using the final trading day of the year to take profits, as the markets were down on Friday. But that shouldn't sour what's been a positive 12 months of trading. The S&P 500 is up more than 11 percent, the Nasdaq has jumped more than 16 percent, and the Dow added 10 percent.
But when it comes to individual stocks, who were the big winners and losers for 2010? "Squawk on the Street" took a look at those during "Six in 60."
Caterpillar was the top-performing stock in the Dow this year, up almost 65 percent.
Netflix was the S&P 500's high-flyer, up over 226 percent.
Baidu.com, China's answer to Google, finished the 12-month period with a 138-percent gain. That was the Nasdaq's best return.
Hewlett-Packard led the Dow with its 18-percent decline.
On the S&P, that honor went to Dean Foods, which fell over 52 percent as a result of higher commodity costs.
And finally, on the Nasdaq Apollo Group was the biggest loser. It slipped 35 percent during 2010.
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