Guaido's arrival in Davos comes exactly one year after the opposition leader declared himself to be Venezuela's rightful interim president.
Venezuela's internationally-recognized government concedes the last 12 months have been "very tough."
Juan Guaido, the leader of Venezuela's internationally-recognized government, was prevented from entering parliament on Sunday.
The South American nation is currently in the midst of one of the worst humanitarian crises in recent memory.
A coup taking down Venezuelan president Nicolas Maduro would be only the first step to get the South American economy back on track. Shock therapy will be required to reverse the chaos of a state-run system that wasted its oil riches.
Venezuela's opposition leader said the talks must lead to a solution of the crisis and must not be used by Maduro's government to buy time.
The United Nations has issued a scathing critique of the human rights situation in Venezuela.
Maduro has intensified a crackdown on subversives and "coup plotters" in the weeks following a failed military uprising attempt on April 30.
Venezuelan President Nicolas Maduro said security forces had foiled an opposition coup attempt that included plans to assassinate him.
Some 4 million people have fled the South American country since 2015 amid an economic meltdown.
CNBC's Jim Cramer says Facebook's new Libra cryptocurrency is a "brilliant" endeavor.
The government of President Nicolas Maduro halted the publication of economic indicators in 2015 as the OPEC nation's socialist system began to unravel in response to the global decline in oil prices.
U.S. crude futures gained on Tuesday after flooding throughout the Midwest constrained crude flow from the main U.S. storage hub in Cushing, Oklahoma.
A Venezuelan general called on the country's armed forces on Sunday to rise up against President Nicolas Maduro, who has relied on the backing of the military to hold on to power despite an economic collapse.
Oil prices fell as renewed doubts over U.S.-China trade talks stoked jitters over global growth, but losses were tempered U.S.-Iran tension.
U.S. Vice President Mike Pence is set on Tuesday to offer new incentives to Venezuela's military to turn against President Nicolas Maduro, responding to an attempted uprising that fizzled out last week, a senior administration official told Reuters.
CNBC's Eamon Javers sits down to discuss the on-going crisis in Venezuela with Vice President Mike Pence.
Gold prices slumped to an over four-month low on Thursday after the U.S. Federal Open Market Committee (FOMC) axed any hopes for a rate cut in the near term, subduing demand for the non-interest bearing bullion.
"There's no turning back," Juan Guaido, opposition leader, said as he addressed supporters on the streets of Caracas on Wednesday.
Venezuelans were expected to take to the streets on Wednesday for what opposition leader Juan Guaido pledged would be the "largest march" in the country's history.