But the government shutdown has shuttered the famous national park and emptied out the surrounding streets, depriving residents of revenue.
"It's disastrous," said Greg Bryan, the manager of a local Best Western hotel who also happens to be the town's mayor. He added that Tusayan is losing tens of thousands of dollars a day—totaling close to a million in much-needed money that business owners likely won't recoup.
(Read more: Small businesses fear bankruptcy from national park shutdowns)
Roughly 4.5 million visitors from around the world venture to the Grand Canyon annually, injecting an estimated $1.3 million a day into nearby towns.
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The Best Western, which is usually 90 percent occupied—especially in October, when cool temperatures throw off the blanket of Southwestern heat—was barely one-third full Tuesday night, Bryan said.
(Read more: Here are 7 debt-default doomsday scenarios)
Many of the hotel's employees—not to mention some 2,200 workers inside the park—have been laid off amid the tense political impasse in Washington.
Now, residents are scrambling to make ends meet after losing jobs that didn't pay all that much to begin with, locals said.
On Tuesday, some 50 people swarmed the entrance sign to Grand Canyon National Park, staging a "fed up with the feds" protest to draw attention to the fiscal crisis plaguing the town, according to the Associated Press.
"The service workers are suffering. They have no pay, no food," said Bill Brookins, a protester. "They are minimum-wage workers. It's wrong."
(Read more: Goats laid off by government shutdown)