Storefront faces challenges if it wants to become as big as Airbnb, the service that links would-be renters with physical vacation properties. One key difference is Storefront is business-facing, as opposed to Airbnb's consumer-facing model, ultimately making it harder to scale.
Read MoreRent your home—or your couch
Another factor to consider is the fact that renting physical space has traditionally not been as easy as clicking "rent" and showing up, the way consumers typically rent a room. Little said nearly all of her clients visit to see her space before agreeing to rent.
"There's still a process (with) a client seeing the space to make sure it's going to be a fit for what they really want," she said.
—By CNBC's Uptin Saiidi