"I am confident that the package of measures we announced in June will indeed provide the intended boost to demand, and we stand ready to adjust our policy stance further," Draghi said in a speech text.
"The Governing Council would use also unconventional instruments to safeguard the firm anchoring of inflation expectations over the medium- to long-term," he said.
He did not, however, add any qualifier this time, such as in introductory remarks at his August news conference when he added: "...should it become necessary to further address risks of too prolonged a period of low inflation".
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The most powerful tool left in the ECB's toolbox are large-scale asset purchases, also known as quantitative easing (QE), although Draghi made no reference to this in his speech.
Draghi expected support for the economy from a weaker euro, a planned scheme to revive Europe's market for securitised loans and the ECB's new long-term loan plan, dubbed TLTROs, for which he said there was "significant interest from banks".
"We have already seen exchange rate movements that should support both aggregate demand and inflation, which we expect to be sustained by the diverging expected paths of policy in the US and the euro area," he said.
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The euro hit its weakest level against the dollar since September 2013 on Friday.
While the euro zone is teetering on the brink of deflation, struggling with stagnant growth and double-digit rates of unemployment, the picture looks more rosy across the Atlantic where the U.S. Federal Reserve has started to rein in stimulus.
The Fed is widely expected to start raising interest rates next year, a move that is seen to push up the dollar and thereby weaken the euro further.