Take a look at some of Wednesday's midday movers:
Royal Caribbean Cruises - The cruise operator and others including Carnival and Norwegian Cruise Lines Holdings climbed on anticipation that a thaw in U.S.-Cuban relations will increase travel between the two countries.
Herzfeld Caribbean Basin Fund - The fund with $25 million in assets soared on news of the thaw in U.S.-Cuban relations.
Netflix - The provider of online entertainment rose after Dish Network said it would begin streaming Netflix movies and TV shows.
Exxon Mobil - The oil producer and competitors including Chevron ConocoPhillips, Hess and Anadarko Petroleum rallied with crude.
OnDeck Capital - The online arranger of small business loans soared in its market debut.
Amgen - The drug developer climbed after it said its new leukemia treatment would cost about $178,000 when it becomes available on Thursday.
NPS Pharmaceuticals - The drug developer gained after Bloomberg reported Shire was considering a bid for the company.
Blackberry - The maker of wireless devices advanced after it launched its long-awaited Classic smartphone device.
American Express - The credit-card company rose after Morgan Stanley began coverage with an overweight rating.
MasterCard - The company and Visa advanced on news that credit and debit cards can now be used in Cuba.
Diageo - The spirit maker fell after giving a lukewarm outlook for the first half of its fiscal year in the U.S.
Auspex Pharmaceuticals - The drug developer surged after saying said its drug for treating chorea, or involuntary movement associated with Huntington's disease, succeeded in a late-stage study.
Digital River - The provider of cloud-based payment solutions rose after it extended a distribution pact with Microsoft.
The Pantry - The convenience-store chain jumped on a Wall Street Journal report that it was nearing a deal to sell itself.
Joy Global - The mining-equipment maker fell after reporting a four percent drop in quarterly revenue.
Pozen - The company declined after it said two versions of its experimental heart drug were rejected for a second time by the Food and Drug Administration.
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