Chase closes accounts of pot entrepreneur Martin Tobias

After more than 20 years of banking with JPMorgan Chase, former Microsoft executive and marijuana entrepreneur Martin Tobias saw his business and personal accounts terminated this week.

Chase spokeswoman Patricia Wexler confirmed that both of Tobias's accounts have been shut down, but as policy she would not give more details about his case.

"We are closely following federal guidance on this matter," she said, explaining that the bank doesn't work with marijuana businesses. "If we find out that someone is in the business after they have already been banking with us, then we take steps to close that account."

Marijuana Canada Cannabis
Harriet Taylor | CNBC

CNBC profiled Tobias this week in a series called "Potrepreneurs: Cashing in on Weed." Tobias got into the cannabis industry when he discovered that a warehouse he owned in Seattle was zoned as legal for marijuana businesses. He received offers on the building from would-be buyers who wanted to grow marijuana there. He decided to sell, but then began to explore marijuana real estate, finally creating South Fork Business Park, an industrial area in Raymond, Washington, catering to pot businesses.

In some cities, including Seattle and San Jose, California, marijuana businesses are legal in areas that are zoned for them.

Read MoreMarketers capitalize on pot's high holiday

Tobias said his project is the largest cannabis real estate development in the United States, at over 750,000 square feet. Tobias also founded the Washington Cannabusiness Association.

Tobias's banking difficulties point to one of the risks of getting into the marijuana industry. Though many states have legalized marijuana to one degree or another, those laws can conflict with federal rules, including those that oversee banks.

"I'm trying to support this newly legal business, I've invested millions of my own money, I have employed people, and the state wants me to be in this business," Tobias said. "The discrepancy and negative consequences between state and federal policy, though, is what turns people off."