The newly split Hewlett Packard Enterprise and HP will transform its business by helping other firms transform theirs, Meg Whitman said Monday.
"Every company, whether it is a small company or a big company, is having to take their legacy IT systems and transform themselves so that IT can be a competitive advantage. How do you turn an idea into a reality in warp speed?" HPE's chief executive officer told CNBC's "Squawk on the Street."
"We are uniquely positioned to help companies do that because we have hardware, software and services, and we are focusing around a small number of problems that are really important to customers."
Following the split of Hewlett-Packard into two separate publicly traded companies on Monday, HP Inc. will sell personal computers and printers, and Hewlett Packard Enterprise will sell commercial computer systems, software and tech services.
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Hewlett-Packard was an early pioneer of what became the model for Silicon Valley start-ups: Founded in 1939 by two Stanford graduates in a Palo Alto, California, garage, HP was long celebrated for its engineering know-how and laid-back corporate culture. It made hefty profits as it grew into a multinational giant that sold a wide range of computer gear and commercial tech services.
But after struggling to keep pace with recent trends like the rise of smartphones and cloud computing. HP's board decided last year to create two smaller companies, each with a narrower focus.
HP recently said it's giving up on competing directly in cloud computing, a growing business in which companies large and small run software in remote data centers operated by Amazon and others.
"The truth is that Amazon and Azure are way out in front in the public cloud, and our view was, is there a way to partner with them while we provide the hybrid environment. It's the classic where to play and how to win, and we decided we had a better chance of being the leader in private cloud," Whitman told CNBC.
Following an extended period during which Hewlett-Packard failed to grow revenues, Whitman said investors will definitely see top-line growth from Hewlett Packard Enterprise in constant currency in 2016.
Asked whether the new, smaller enterprise services-focused company would become a takeover target, Whitman said, "I've got a lot of confidence, but you never what's going to happen. This is a very dynamic environment."
Investors should not expect any additional layoff announcements from the two companies, Whitman added. In September, Hewlett-Packard announced it would let go 25,000 to 30,000 employees, primarily in enterprise services. The moves increased the share of the company's employees working overseas.
Read MoreLayoffs needed because market is changing so rapidly: HP's Whitman
Whitman acknowledged that the personal computer sales market has been volatile recently, but said she was excited about the prospects for the hardware-focused HP Inc. under CEO Dion Weisler
"Dion has done what most companies need to do, which is in a down market you have to gain share, and he has done that, so you can't argue with how he has run the company," she said.
Whitman will chair the board of directors for HP Inc.
—The Associated Press contributed to this story.