Take a look at some of Tuesday's midday movers:
OncoMed Pharmaceuticals surged on news Celgene would help it develop and market six of its experimental anti-cancer stem-cell drugs.
Myriad Genetics fell on reimbursement and competitive pressures. Medicare recently said it would reduce payments for breast cancer gene tests.
Walt Disney fell after B Riley downgraded the stock to neutral from buy, citing valuation.
Groupon rose after it announced record holiday weekend sales in North America.
Mondelez moved higher after it boosted its stock buyback by $1.7 billion to $7.7 billion.
Raytheon rose after the defense contractor forecast as much as $5 billion in Mideast orders in a matter of weeks.
Deckers Outdoor gained after Canaccord raised its price target $10 to $91 a share, citing accelerating sales.
Abercrombie & Fitch climbed as Engaged Capital, which owns less than 1% of the company, called on the teen apparel retailer to replace longtime CEO Mike Jefferies when his contract expires in February.
Imax fell after Goldman Sachs cuts its rating to neutral from buy, citing valuation.
General Motors, Ford and Toyota all fell after reporting better than-expected November car sales.
Ascena climbed after the women's apparel retailer reported a five percent rise in first-quarter sales as more customers shopped at its Lane Bryant and Justice brand stores.
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—By CNBC's Rich Fisherman.
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