As Indian Prime Minister Narendra Modi welcomes Chinese counterpart Xi Jinping to his home town state of Gujarat on Wednesday, analysts say the meeting between the leaders of the economic titans will be the most significant in decades.

"This meeting… will be the most significant since Rajiv Gandhi's visit to China in 1988. That visit cooled the rising border tensions between India and China and set the stage for the boom in mutual trade that followed," Anil Gupta, Michael Dingman Chair in Strategy, Globalization and Entrepreneurship at the Smith School of Business at the University of Maryland, told CNBC.