New York state now has more cases than any other state in the U.S. as the number of newly confirmed infections surged by 30% overnight to 421, New York Gov. Andrew Cuomo said Friday.

"This is not going to be a quick situation. This is going to be weeks, months," Cuomo said at a press conference in Albany, N.Y. "My guess is there are thousands and thousands of cases walking around the state of New York."