Sure, it's hard to turn down opportunities when you're just starting out, but saying yes to everything and getting stressed out isn't the way to go, she said.
"We want to be very prolific, but I think when you spread yourself too thin, you don't give yourself to it," she said.
While she's been in the public eye her entire life, Barrymore was deliberate in transitioning into business ventures outside of Hollywood. She launched Flower Beauty in January 2013 as an exclusive cosmetics line for Wal-Mart, manufactured by Maesa. She has since launched Flower Eyewear, and is now expanding into online retail and international markets.