Melody McCloskey entered the start-up scene as a 26-year-old female entrepreneur trying to build an online platform in the beauty industry.
She had no software engineering background, was not part of an accelerator program, and had few mentors.
The odds were stacked against her, and she knew it.
"I was in an industry where it's mostly people who don't look like me building companies that aren't like the company I'm building," McCloskey told CNBC.
Within five years, McCloskey co-founded StyleSeat, an on-demand beauty appointment booking company. StyleSeat has raised $40 million in venture capital funding and has done $3.2 billion in cumulative sales.
"In the beginning I was definitely overwhelmed with all of the reasons why I shouldn't do it," she said. Here are the two main thoughts she had to ditch to become successful.