Mad Money has formalized the ever-constant debate between technical analysts and fundamentals-based investors, creating the weekly segment Off the Charts. Cramer pits chartologists against those such as himself, who study the underlying business when evaluating a stock. This week’s battleground: Sepracor.

One school thinks this stock is going higher, and one predicts the opposite. Watch the video as Cramer explains how downtrend lines, moving averages, patent expirations and the company’s drug pipeline affect this stock. And find out whether he thinks SEPR is a buy or sell.

Call Cramer: 1-800-743-CNBC

Questions for Cramer?

Questions, comments, suggestions for the Mad Money website? madcap@cnbc.com