David Cameron has complained to his Chinese counterparts about their treatment of GlaxoSmithKline, the U.K. drugs company that has found itself caught in the center of a storm over allegations it bribed Chinese doctors to sell its medicines.
The prime minister raised the issue during meetings with China's top politicians in Beijing on the first day of a three-day trade mission to the country.
(Read more: GSK's China sales topple on bribery scandal)
A Number 10 official said: "The prime minister discussed British business interests in China and the need for them to think China is a secure and stable environment for them to operate in."
GSK's medicine and vaccine sales in China have dropped 61 percent since the summer, following the high-profile corruption probe launched by Beijing into the pharmaceutical company's alleged business practices.