Check out which companies are making headlines before the bell:
Synageva BioPharma–The drug maker will be acquired by Alexion Pharmaceuticals for $8.4 billion in cash and stock, valuing Synageva at $230 per share. That's well above Synageva's Tuesday closing price of $95.87 per share.
Vitamin Shoppe–The nutritional products retailer fell 11 cents short of estimates with quarterly profit of 63 cents per share, with revenue also below analyst forecasts. The company also cut guidance for the year, saying it was facing a combination of "external headwinds and margin pressure".
American Express–The stock was upgraded to "outperform" from "market perform" at Bernstein, which said the company's risk/reward is "dramatically skewed" to the upside.
GlaxoSmithKline–The drug maker's revenue was in line with estimates, but its earnings were short of forecasts. Glaxo had better than expected results for vaccines and consumer health care, but pharmaceuticals were a drag on profits.
Wendy's– The restaurant chain earned an adjusted 6 cents per share for its latest quarter, one cent above estimates, though revenue was below forecasts. Wendy's also announced plans to sell its bakery operations during this quarter, and will refinance its existing debt.
Mylan–Mylan adjusted quarterly profit of 70 cents per share, one cent above estimates. Revenue was below estimates, impacted by the strong dollar. Activity in Mylan's stock has been driven recently by a three-way takeover battle in which it is trying to buy Perrigo while fending off a takeover bid from Teva.
News Corp.– News Corp. missed estimates by a penny with adjusted quarterly profit of five cents per share, with revenue essentially in line. The Wall Street Journal owner was hurt by foreign currency issues as well as a drop in newspaper ad sales.
Allstate–Allstate reported adjusted quarterly profit of $1.46 per share, two cents above estimates, with revenue in line. The earnings beat came as catastrophe related claims fell significantly.
Electronic Arts–Electronic Arts beat estimates by 14 cents with adjusted quarterly profit of 39 cents per share, while revenue was well above Street forecasts. The video game maker was helped by the release of a new game, "Battlefield Hardline", and also saw an increase in digital sales.
Groupon–Groupon came in 2 cents above estimates with adjusted quarterly profit of three cents per share, though revenue was well below estimates and the daily deals provider also gave weak current quarter guidance. Groupon is seeing weaker billings and is also being hurt by the strong dollar.
Herbalife–Herbalife earned an adjusted $1.29 per share for its latest quarter, beating forecasts by 29 cents, with revenue in line. The nutritional products maker also raised its full-year profit forecast as its business in China improves.
LendingClub–LendingClub doubled estimates with adjusted quarterly profit of two cents per share, with revenue exceeding forecasts as well. The online lender was helped by higher transaction fees, and it raised its revenue forecast for the full year.
Papa John's–The pizza chain reported quarterly profit of 55 cents per share, two cents above estimates, and its revenue was above forecasts as well. The results were driven by higher comparable sales and new unit openings.
Weight Watchers–Weight Watchers lost 9 cents per share for its latest quarter, smaller than the 19 cent loss the Street was expecting. Revenue came in slightly below estimates, as the weight loss company struggles to hold onto both in-person meeting members and online subscribers.
Zulily–Zulily reported an unexpected profit of one cent per share, with analysts having forecast a three cent per share loss. Revenue was below estimates, however, and the retailer gave weaker than expected revenue guidance for the current quarter and the year.
Noodles & Co.–Noodles missed estimates by 2 cents with adjusted quarterly profit of 3 cents per share, with the restaurant chain's revenue also missing the mark and the company giving a weak earnings forecast for the full year. Noodles saw an 8.6 percent drop in royalty and fee revenue from franchisees compared to a year earlier.
JPMorgan Chase–The bank is in advanced talks with government officials and the Federal Reserve to resolve investigations into its foreign exchange trading.
Sears Holdings–The retailer is no longer offering the Kardashian Kollection, with the family reportedly saying they believe Sears is a "sinking ship".
Salesforce.com–Salesforce is on watch once again today on takeover talk, with Bloomberg reporting that Microsoft is considering a bid for the provider of customer service software.
ABInBev–The beer brewer reported a sharp jump in first quarter profit, despite weak demand in the U.S. and negative impact from the strong dollar.