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U.S. Treasury yields rose after trading lower following the Treasury Department's auction of $24 billion in 10-year notes at a high yield of 2.237 percent.
Benchmark 10-year Treasury note yields traded at 2.2756 percent after trading around 2.26 percent after the sale. They rose as high as 2.2783 percent.
Thirty-year U.S. bond yields traded at 3.0715 percent after trading around 3.04 percent following the sale. They rose as high as 3.0676 percent.
The sale's bid-to-cover ratio, an indicator of demand, was 2.72, slightly higher than a recent average of 2.66.
Indirect bidders took 60.2 percent, higher than a recent average of 51 percent, while direct bidders made up 20.9 percent.
"Bottom line, a yield around the highest level since December brought out the buyers and the 10-year yield is falling to 2.24 percent from 2.26-.27 percent just prior. We'll soon see if this creates a ceiling now in yields at the 2.25-2.30 percent. At the same time we'll soon see whether we've actually created a new floor for rates too," Peter Boockvar, chief market analyst at The Lindsey Group, said in a note.
Earlier, U.S. Treasury yields fell following the release of numerous U.S. economic data points.
Retail sales in the U.S. remained unchanged in the month of April, while analysts expected a 0.3 percent increase. U.S. business inventories for March also came in below expectations, rising 0.1 percent versus a 0.2 percent estimate.
The U.S. government also reported that import prices fell for a 10th straight month in April, likely reflecting the impact of a strong dollar, a sign of benign inflation pressures that could encourage the Federal Reserve to delay raising interest rates.
The Labor Department said on Wednesday import prices fell 0.3 percent last month after slipping 0.2 percent in March.
A $24 billion auction of three-year bonds, the first sale of a total $64 billion in new paper to be sold this week, was met with decent demand.
On Thursday, the Treasury Department will sell $16 billion in 30-year bonds, concluding this week's offerings.
The yield on 10-year German Bunds rose to 0.7230 percent after rallying Tuesday.
—Reuters contributed to this report.