There's a ton of uncertainty ahead of the referendum vote in Greece on its bailout measures Sunday.
A "yes" vote to creditors' terms should mean Greece stays in the euro and the common currency will jump for the week.
A "no" vote could lead to an exit by the country from the currency and spark fears that other nations like Spain may follow.
For U.S. investors, trading the euro directly may be a risky and volatile game. However, once the currency finds a direction, there are certain derivative plays that history shows could be profitable.
Using Kensho, a quantitative tool used by hedge funds, CNBC Pro looked at all the times in the last decade when the euro jumped significantly against the U.S. dollar during a one-week period.
Specifically, there have been 30 times since 2005 when the euro/U.S. dollar surged 2.5 percent or more in five days.
Five exchange-traded funds performed very well when the euro jumped...