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Mayer: We'll make Yahoo the best it can be

Yahoo CEO: Coming from position of strength
Yahoo CEO on potential sale
Marissa Mayer: Confident we can grow revenue

Yahoo CEO Marissa Mayer on Wednesday said she is focused on making the company the best it can be.

"That's being focused on discovering, being the digital information guide that we've always been, and really thinking through how can we inform, connect and entertain our users," she told CNBC's "Squawk on the Street" one day after Yahoo announced it would explore strategic alternatives.

Specifically, Mayer said Yahoo would continue to focus on mail, search and its Tumblr service as global platforms and push its news, sports, finance and lifestyle verticals in particular geographic areas.

"Making Yahoo the very best version of itself we can for our users, for our advertisers is really what's going to serve our shareholders best," she said.

Yahoo's shares were more than 7 percent lower Wednesday morning following her comments. (Get the latest quote here.)

Yahoo on Tuesday announced it would consider a reverse spinoff and cut about 15 percent of its workforce as part of a restructuring to boost a sluggish core business.

Yahoo has weighed its next strategic moves amid a rough stretch for its Internet business and stock price. If it chooses a reverse spin, the company would effectively separate its core assets from its lucrative stake in Chinese e-commerce giant Alibaba.

In addition to the layoffs, which are expected to happen in the first quarter, Yahoo plans to close five offices. The company hopes to trim operating expenses by more than $400 million by the end of the year.

Mayer said she believes Yahoo is now in a position of strength after building mobile operations with 600 million monthly users and a billion dollar advertising business.

She said it makes sense for Yahoo to have a "more reasoned perspective" in terms of how quickly it can advance its plan.

"We've gotten some of those precursors in place. I now understand how long it's taken us to do that and do it really well, and also how we can move forward and really propel ourselves from here," she said.

During her tenure, the embattled Mayer has focused on growth in mobile, video, native advertising and social. For the fourth quarter, the collective "Mavens" businesses saw $472 million in sales, up from $375 million in the previous year.

Still, Mayer acknowledged that the company had failed to improve EBITDA — or earnings before certain expenses — as it said it would in 2014.

The tech company's quarterly results Tuesday were broadly in line with analysts' expectations. Yahoo posted adjusted fourth-quarter earnings of 13 cents per share on $1.27 billion in revenue. However, its net loss came in at $4.44 billion due to a goodwill impairment.

Mayer said she felt it was important to once again acknowledge that, in executing the strategic plan for 2016, revenue and EBITDA would likely be down as Yahoo deals with headwinds in its legacy business.

She also reiterated that Yahoo expects to see slowdown in growth in Mavens business, which grew 44 percent year over year in 2015.

Overall, Yahoo's strategy has been to hold revenue flat to slightly negative as it works to establish new lines of business that can carry the company forward, she said.

Disclosure: CNBC has a content-sharing partnership with Yahoo's finance site.